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Some medications and supplements are offered without adequate warnings about their limitations

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Examples of PPIs: Here are some PPIs that may interact with levothyroxine: esomeprazole (Nexium) omeprazole (Prilosec) pantoprazole (Protonix) Steps you or your doctor may take: If you take levothyroxine with a PPI, your doctor will likely monitor you closely to make sure levothyroxine is working for you