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Biological role of matrix stiffness in tumor growth and treatment

In CD4 T helper cells, the 1,25(OH)DVDR axis suppresses Th1/Th17-associated cytokines such as IFN-, IL-17 A, and IL-22, while upregulating Th2-related cytokines including IL-4, IL-5, and IL-13, thus promoting a functional shift toward Th2 polarization [163,164,165]

Cell culture Human HCC cell lines MHCC97H, HepG2 and PCa cell line DU145 were cultured in high-glucose DMEM complete medium with 10% fetal bovine serum (FBS