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*Correspondence: Linlin Hao, [email protected] This article was submitted to Signaling, a section of the journal Frontiers in Cell and Developmental Biology Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

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This history of failures - both recent and distant - underscores the immense magnitude of our recent breakthrough, transforming it from a simple innovation into a story of scientific redemption