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Life events such as stress or trauma may serve as epigenetic modifiers (meaning they modify gene expression and function without altering the sequence of specific genes) that impact serotonin, dopamine, and glutaminergic pathways (Pauls 2014

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Thus, miR-124a2 can directly modulate insulin expression through foxA2 and then pdx1

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In the following, we review the preclinical and clinical evidence of GIP receptor antagonism

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