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Abstract Glucagon-like peptide-1 receptor agonist (GLP-1RA), a novel hypoglycemic agent for the treatment of type 2 diabetes, has well-known effects such as lowering blood sugar, ameliorating inflammation, reducing weight, and lowering blood lipids

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The dual action synergistically suppresses hepatic de novo lipogenesis while promoting lipid catabolism, resulting in a net reduction of hepatic steatosis (41, 42)