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However, the compound became widely available for routine use in the treatment of B12 deficiency in the early 1950s (8)

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Notably, GS, as a pivotal astrocytic enzyme, maintains glutamatergic-GABAergic equilibrium by converting synaptically released glutamate into glutamine, thereby preventing excitotoxicity and sustaining inhibitory GABA synthesis [42, 43]

Cells were maintained at 37C in a humidified environment containing 5% CO 2

Dipeptidyl Peptidase IV Inhibitor Sitagliptin Reduces Local Inflammation in Adipose Tissue and in Pancreatic Islets of Obese Mice