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And in a twist that makes the insomnia narrative even more confusing, the FDA actually approved tirzepatide for treating obstructive sleep apnea, one of the most common sleep disorders on the planet, making it the first and only prescription medication approved for that specific indication

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Clinical trials lasting 68 weeks showed that participants on semaglutide maintained significant weight loss throughout the treatment period, with continued improvements in metabolic markers including blood sugar, blood pressure, and cholesterol levels

This mechanistic insight provides a modern conceptual basis for integrating TCM approaches into DKD management (232)

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