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Moellering et al., 1999

Historically the "first exercise mimetic" to receive media attention

Dula also significantly reduced the expression of transforming growth factor-1 (TGF-1), phosphatidylinositol-3-kinase (PI3K), protein kinase B (AKT) signaling pathway, and the inflammatory cytokines: nuclear factor kappa B (NF-B), interleukin-6 (IL-6), and interferon- (IFN-) in colonic cellular structures

A pair of studies examined the outcomes of people at high risk of cardiovascular disease who underwent heart-related procedures

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