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Systematic capture of dosing patterns, formulation source, route of administration, and standardized clinical outcomes may be more informative than continued reliance on heterogeneous mechanistic studies

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Because it does not rely on appetite suppression, it is an excellent intervention for patients who are already eating clean, hypocaloric diets but remain unable to alter their body composition

tirzepatide lowered HbA 1c by 2.01 to 2.30 percentage points versus 1.86 for semaglutide, meeting non-inferiority and superiority, with greater weight loss as well

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