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28,29 Koike et al reported that treatment with vitamin C prevented cigarette smoke-induced emphysema and restored lung tissue damage in protein-30 knockout (SMP30-KO) mice characterized by accelerated aging

Given that limited capacity of self-renewal in neurons (Sorrells et al., 2018), targeting neuronal death by neuroprotection holds promise in neurological disease therapy (Neuhaus et al., 2017)

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In adolescent male rat models exposed by the Delta-9-tetrahydrocannabinol (THC), L-theanine could strongly block the development of emotional and cognitive abnormalities associated with adolescent THC exposure, since L-theanine pretreatment could intercept THC-induced downregulation of local GSK-3 and Akt signaling pathway in the prefrontal cortex (PFC) (54)

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