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2.1 Pharmacological effects METH is a lipophilic compound that rapidly crosses the blood-brain barrier (BBB) and accumulates in the brain

Liu T-C, Gurram B, Baldridge MT et al (2016) Paneth cell defects in Crohns disease patients promote dysbiosis

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10.1016/s0893-133x(02)00306-8 Neuropsychopharmacology 124 TothE.HarsingL

31,32 Moreover, Li et al argue that the initial cytokine storm and neuroinflammation caused by the virus can disrupt neural circuits and their connections leading to vast neurotransmitter changes