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In this narrative review, we summarized the current evidence and ongoing studies on the mechanism of action, clinical pharmacology, and applications of amylin and its analogs, pramlintide and cagrilintide, in the field of diabetology, endocrinology, and metabolism disorders, such as obesity

Implications of the DSIP-GILZ Connection: Stress Resilience: The GILZ protein is upregulated by dexamethasone (a potent corticosteroid) as a negative feedback mechanism to control inflammation

22 However, none of these systems appear to still be in clinical development

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