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Table of Contents Why GLP-1 Medications Cause Constipation Glucagon-like peptide-1 (GLP-1) receptor agonists, including semaglutide (Ozempic, Wegovy), dulaglutide (Trulicity), and liraglutide (Victoza, Saxenda), are increasingly prescribed for type 2 diabetes management and weight loss

The B-12 shot is used for the metabolism of fats, proteins, and carbohydrates

Approximately 0.1% of this is lost per day by secretions into the gut, as not all these secretions are reabsorbed

Older adults often struggle with absorption because stomach acid production decreases with age

Companies that recommend morning dosing either haven't read the endocrinology literature or are prioritizing compliance over outcomes