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Serum tryptase the most commonly used diagnostic marker for mast cell activation may be normal in non-clonal MCAS even during symptomatic periods, and many of the mediators most relevant to MCAS (prostaglandin D2, leukotriene E4, histamine metabolites) require specialized urine testing that is not part of routine clinical evaluation

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Regulatory note: Melanotan II is not approved by any major regulator an unapproved new drug sold as a research chemical, not a medicine [6]

This means GLP-1 medications can directly influence how your salivary glands function, independent of hydration status