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[27], [36] Human RPLPO (large ribosomal protein) and PGK1 (phosphoglycerate kinase 1) were run as endogenous controls

4.4 Neonatal hypoxicischemic encephalopathy The pathophysiology of HIE involves hypoxicischemic injury, characterized by perturbations in mitochondrial dynamics and the inhibition of critical energy-producing pathways, including oxidative phosphorylation and fatty acid -oxidation ( -oxidation and its prior neuroprotective effects in adult ischemia models, it represents a biologically plausible candidate for investigation in neonatal brain injury

Drugs targeting TNF- or its pathway, like infliximab and etanercept, showed mixed results in improving insulin sensitivity, with some success observed over longer treatment periods (Kueck et al., 2023

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