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NAD+ supplements (typically NR or NMN) raise cellular coenzyme levels, whilst retatrutide is an unlicensed investigational triple receptor agonist (GLP-1, GIP, glucagon) not yet approved by the MHRA or EMA for use in the UK

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Hassan C, Antonelli G, Dumonceau JM, Regula J, Bretthauer M, Chaussade S et al (2020) Post-polypectomy colonoscopy surveillance: European Society of Gastrointestinal Endoscopy (ESGE) Guideline Update 2020

While many side effects alleviate over time, some require closer monitoring and treatment