As a cause-effect relation, vascular failure may occur even before full acute pancreatitis presentation with a severe occlusion-like syndrome, peripherally and centrally
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The dosing regimen varies depending on whether neurological symptoms are present: With neurological involvement: 1 mg intramuscularly on alternate days until no further improvement, then 1 mg every 2 months [3] [4] Without neurological involvement: 1 mg intramuscularly three times a week for 2 weeks, then 1 mg every 2-3 months for maintenance [3] [4] There is some evidence that high-dose oral B12 (1000-2000 micrograms daily) may be effective even in some malabsorption conditions, though UK practice still generally favours intramuscular treatment in these cases
When the body fails to absorb vitamin B12, various health issues can be witnessed, including permanent neurological changes and fatigue
