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27 This action should probably also be considered because NO can also be produced by the inducible NO synthase of activated macrophages and neutrophils

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2 Low-resolution techniques in the discovery of IDPs Although the role of NMR in understanding the dynamic nature of IDPs/IDRs and characterization of their conformational ensembles is undeniable and it illuminates intrinsic disorder (Dyson and Wright, 2021), very important information, especially in the early days of the IDP field, was derived using a wide spectrum of low-resolution techniques