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Induction of apoptosis in AML by HA14-1, A cell-permeable organic compound identified by protein structure-based computer screening that binds the BH1 to BH3 surface pocket of Bcl-2

Treusch, G

L 1 and L H also facilitate the expression of p21 and Noxa

Research demonstrates that TB-500 induces hair growth through enhanced stem cell migration and differentiation, with studies showing TB-500-overexpressing mice achieve complete hair regrowth in 11 days compared to 13 days for wild-type controls and 16 days for TB-500 knockout animals, indicating dose-dependent effects on follicle cycling kinetics

10.1186/s40168-017-0293-3 425 TanelianA.NankovaB.CheriyanA.ArensC.HuF.SabbanE