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the ALC chemical structure can be easily absorbed in the gastrointestinal tract
Finally, electrophilic diazenium diolates were designed as prodrugs for spontaneous nitric oxide (NO) release at physiological pH, after a reaction with GSH catalyzed by GST
Finally, ASK1 displayed no detectable HDX changes in any of the tested complexes, in agreement with the structural data (Supplementary Fig
These may include small molecules targeting GPX4, SLC7A11, or ferritinophagy regulators like NCOA4, as well as compounds modulating iron metabolism or lipid peroxidation
Prescreening is recommended, and these agents should not be used in patients with chronic hepatitis B
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