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The Rationale for Combination: Complementary Mechanisms The appeal of combining these medications lies in their different ways of tackling weight loss: Topiramates Neurological Impact: By affecting brain chemicals, Topiramate can help curb cravings and reduce the desire for food

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GLP-1 receptor agonists are not licensed specifically for fatty liver disease in the UK

Systematic reviews on GLP-1 and gut microbiota Several systematic reviews have examined the relationship between GLP-1 receptor agonists and the gut microbiome