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Study 2: Selective Small-Molecule Inhibitors (including 5-Amino-1MQ) A selective, membrane-permeable NNMT inhibitor series decreased intracellular 1-MNA, increased NAD and SAM, suppressed adipocyte lipogenesis, and reversed high-fat-diet obesity in mice

Vitamin B12 is water-soluble, meaning your body will typically eliminate any excess through urine

The study was supported by a National Institutes of Health (NIH) grant HD084422 to D.M.-R

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