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Chinese medicine has long used various herbs under this umbrella for addressing hormonal imbalances, fatigue, sexual dysfunction, mood swings, and many other issues common to menopause

Journal of Chromatography A , 1265, 57-69

First, endothelial dysfunction develops through TNF-/IL-1-mediated eNOS suppression, ROS-mediated NO depletion, ET-1 and angiotensin II activation, RhoA/ROCK signaling, AGERAGE/NF-B amplification, and sympathetic catecholamine-driven vasoconstriction (157159)

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However, there was no change in nerve conduction or sensory function