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Glutathione peroxidase 2 and aquaporin 8 as new markers for colonic inflammation in experimental colitis and inflammatory bowel diseases: an important role for H2O2

The peptide is considered a compound due to its multi-target activity across vascular, structural, and inflammatory pathways in connective tissue healing

The most parsimonious framing is a three-axis model: Transcriptional axis (GHK-Cu): upregulates VEGF, bFGF, collagen and elastin transcripts