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In early trials, people also saw benefits beyond weight loss, including: Better blood sugar control (lower HbA1c levels) Reduced blood pressure Improved cholesterol Lower levels of liver fat To learn more about retatrutides wider benefits, see our Retatrutide benefits article How long before retatrutide works Retatrutide tends to start working within 2 to 4 weeks

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It targets three key receptors : GLP-1, GIP, and glucagon receptors