The mechanisms that implicate the declining of age-related ascorbate are complex and involve multiple cell signaling pathways such as accelerated turnover, increased usage, reduced cellular uptake, and decreased absorption/reabsorption
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doi:10.1021/cr2001178 Xia F, Zuo X, Yang R, Xiao Y, Kang D, Valle-Blisle A, Gong X, Yuen JD, Hsu BBY, Heeger AJ, Plaxco KW (2010) Colorimetric detection of DNA, small molecules, proteins, and ions using unmodified gold nanoparticles and conjugated polyelectrolytes
" What the Clinical Trial Found The randomized clinical trial included 98 adults experiencing severe anhedonia alongside depression and anxiety