Soluble fiber from whole grains and vegetables slows stomach emptying and promotes the gradual release of satiety signals, which overlaps with what GLP-1 medications do
In healthy humans, GIP has a circulating half-life of 7 min (Meier et al., 2004b), GLP-1 has a circulating half-life of 12 min (Deacon et al., 1995b), and GLP-2 has a circulating half-life of 7 min (Drucker et al., 1997
While these medications are highly effective for weight loss and metabolic health, they must be managed carefully during acute illness
In one 2024 study, high levels of glucose and triglycerides and low levels of high-density lipoproteinwhich are usually signs of worse metabolic healthwere associated with future risk of depression and anxiety ( JAMA Network Open , DOI: 10.1001/jamanetworkopen.2024.4525)
By slowing gastric emptying, enhancing feelings of fullness, and reducing hunger, it helps you consume fewer calories without feeling deprived