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This creates a tension between therapeutic intensity and tolerability that is less pronounced in diabetes care

This can be helpful if your nausea is accompanied by acid reflux or an upset stomach

This often includes a reduction in cravings and an increased feeling of fullness following meals

So this demonstrates the need that future trials should have an active comparator or some other clever study design like an open label extension

Adding new entrants with differentiated mechanisms (like cAMP bias) means your pharmacy and therapeutics committees will need better data infrastructure to evaluate options and guide prescribing