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The activation of cAMP-PKA signaling in gut IELs can inhibit the phosphorylation of Zeta-chain-associated protein kinase-70 (ZAP-70), stopping the signal from TCR, resulting in the inhibition of the immunological response of T cells (Wong et al., 2022
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However, substantial heterogeneity across the studies indicated considerable uncertainty in this estimate
Targeted ablation of glucose-dependent insulinotropic polypeptide-producing cells in transgenic mice reduces obesity and insulin resistance induced by a high fat diet
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