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The role of antioxidants such as Prdx2 in RBCs are only beginning to unravel

Neog MK, Rasool M

Reduce frequency if sensitivity occurs

In vitro , iron chelation with deferoxamine mimics these effects, inducing dose-dependent eryptosis in human erythrocytes, confirming iron depletion per se primes RBCs for apoptotic death (Kempe et al., 2006)