If something isnt working or if a concern arises the protocol changes
Doses up to 60mg/kg per day produced no observable toxicity
Cell culture studies using adipocytes have shown that NNMT overexpression promotes lipid accumulation and insulin resistance, while NNMT knockdown or inhibition increases NAD+ levels, activates SIRT1, enhances mitochondrial respiration, promotes expression of thermogenic genes including UCP1, and drives white adipocyte browning toward a beige phenotype
NNMT inhibition increases adipose [S-adenosylmethionine (SAM)] and [Nicotinamide adenine dinucleotide (NAD+)] levels As youll discover later on in this article, theres a good reason why increased production of SAM and NAD+ within fat cells is beneficial
(Source: National Institutes of Health National Center for Biotechnology Information, 2021) NAD+ supports how your cells produce energy, playing a key role in metabolism, DNA repair, and brain functionhelping you feel sharper and more balanced