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Common Side Effects The most frequently reported side effects include: Nausea, vomiting, diarrhea, constipation Abdominal pain and bloating Headache and fatigue Dyspepsia (indigestion) and heartburn Dizziness Injection site reactions (redness, itching, swelling) Seek Immediate Medical Attention For Severe, persistent abdominal pain (possible pancreatitis) Lump or swelling in the neck, hoarseness, trouble swallowing, or shortness of breath (possible thyroid tumor) Signs of a serious allergic reaction: swelling of face, lips, tongue, throat

If you experience severe right-upper-abdominal pain or jaundice, seek medical evaluation

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While the first injection medication was not much more effective than some of the oral medications available at the time, this all changed when doctors and patients found increased effectiveness of the drugs with the introduction of Wegovy in 2021

Weeks 1 through 4 are relatively mild for most people