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The FDA-approved maximum for weight loss is 2.4 mg weekly, though some patients achieve significant results at lower doses such as 0.5 mg, 1.0 mg, or 1.7 mg

(1995) Biochemistry 34 : 16838-16851 PubMed: 8527460 Search on PubMed DOI: Primary Citation Related Structures: 1LBS, 1LBT PubMed Abstract: Many lipases are potent catalysts of stereoselective reactions and are therefore of interest for use in chemical synthesis

[9] High-dose niacin (used to treat cholesterol) lacks human safety data in pregnancy and could theoretically affect the fetus (for example, by causing hypotension or altering lipid metabolism)

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