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Gastrointestinal side effects such as nausea, heartburn, and constipation may be severe

You can report any side effects directly via the Yellow Card Scheme, which can help provide more information on the safety of any medication

Retatrutide was excluded in trial participants who were pregnant, and there is no safety data for any of the GLOW components during pregnancy or lactation

Key Factors That Influence How Quickly Side Effects Resolve Dosing strategy significantly affects tolerability

Glucagon is traditionally known for raising blood sugar, but in this specific tri-agonist configuration, sustained glucagon receptor activation drives thermogenesis (energy expenditure) and promotes lipid oxidation in the liver