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Notably, the G/D-CuP group showed the lowest ratio of CD86-positive macrophages/CD206-positive macrophages, indicating an enhanced M1-to-M2 transition (Supplementary Fig

106 Following pioneering studies that linked CBS overexpression with colorectal and ovarian cancer (Table 1), an increase in the expression of all enzymes involvedindividually or jointlyin the synthesis of H 2 S has also been reported for breast, gastric, lung, liver, bladder, kidney and prostate carcinomas, melanoma, neuroblastoma, glioma and astrocytoma

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