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Astrup A, Carraro R, Finer N, Harper A, Kunesova M, Lean ME et al (2012) Safety, tolerability and sustained weight loss over 2 years with the once-daily human GLP-1 analog, liraglutide

Consistent access to therapy is also essential, as interruptions can worsen GI symptoms and reduce adherence

This research theorized that hyperglycemia can lead to a downregulation of GIPr causing decreased GIP response despite therapeutic or even supratherapeutic levels of GIP [21]

Tirzepatide (Mounjaro/Zepbound) stood out for joint pain: Posts broadly referencing tirzepatide mentioned joint pain more than twice as often (1.69%) as semaglutide-based drugs

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