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doi: 10.3389/fimmu.2025.1690068 Received 21 August 2025 Accepted 03 October 2025 Published 16 October 2025 Volume 16 - 2025 Edited by Adil Rasheed, Augusta University, United States Reviewed by Zhi-Wei Wang, Wenzhou Medical University, China Yang Xiang, Peking Union Medical College Hospital (CAMS), China Updates Copyright 2025 Yang, Li, Shi, Zhong and Xiong

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Without adequate hydration, bowel regularity, bile flow, and renal clearance, toxin removal is incomplete regardless of how well Phases 1 and 2 are functioning