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Traditional treatment involves the use of supportive therapy, which decreases the symptoms

Novo Nordisk, the manufacturer of Ozempic, says it has experienced "stronger than anticipated demand" leading to worldwide shortages

These include orlistat, phentermine-topiramate (FDA-approved only), naltrexone-bupropion, liraglutide, setmelanotide, semaglutide, and tirzepatide [9, 10]

Notably, GLP-1 RAs also tend to promote growth of genera known for supporting gut barrier integrity (such as Akkermansia ), further hinting at a positive remodeling of the gut ecosystem (34, 35)

Find out at Obesity: A Worldwide Pandemic with Advancing Management Options . Novo Nordisk: The Pioneer in GLP-1 Therapy Novo Nordisk, the pharmaceutical giant, revolutionized weight loss treatment by pioneering GLP-1 receptor agonists