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Finally, aliquot (3-L) of the deproteinized sample was analyzed by means of an ultra high-performance liquid chromatography triple quadrupole mass spectrometry (UHPLC-MS/MS)

Metabolism and immunotherapy Metabolite-mediated immune evasion Besides targeted therapy, immunotherapy is a parallel treatment approach for melanoma patients, regardless of BRAF status, by triggering the cytotoxic potential of the powerful immune system to eliminate tumor cells

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Summary In conclusion, discontinuing glutathione supplementation can lead to a reverse of skin whitening, reduced antioxidant protection, and an impact on immune function