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When IGF-1 LR3 binds to the insulin receptor, it activates a complex signaling pathway that triggers protein synthesis, glucose uptake, and amino acid uptake within muscle cells

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Pregnant and breastfeeding women and those with chronic medical conditions or who are taking medication should consult their doctor or therapist before use

NICE guidance emphasises the importance of investigating the underlying cause of B12 deficiency rather than simply treating with supplements, as this may identify serious conditions requiring specific management

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