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Baseline testing before starting, follow-up at 6 and 12 weeks during dose escalation, then every 3-6 months for ongoing monitoring

Dose escalation can be delayed by 1 week or altered to a more gradual dose escalation if GI intolerance is continued [12, 87], as extending time between dose escalations can help mitigate tolerability issues

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The steepest weight loss phase occurs between weeks 12 and 24

Applying a warm compress for two minutes before injection dilates blood vessels slightly, then applying ice afterward constricts them to slow bleeding