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Safety, pharmacokinetics, and preliminary assessment of efficacy of mecasermin (recombinant human IGF-1) for the treatment of Rett syndrome

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In total, 12 trials from SMART-C were assessed, with the analysis cohort restricted to trials exclusively enrolling participants with diabetes, and participants with diabetes enrolled in the following heart failure and chronic kidney disease trials: DAPA-CKD, EMPA-KIDNEY, DAPA-HF, EMPEROR-Reduced, EMPEROR-Preserved, and DELIVER

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Kuwakado, S