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Caution is advised in patients with a history of pancreatitis, and these medications should be avoided during pregnancy or discontinued well before planned conception (e.g., 2 months before planned pregnancy for semaglutide based on its half-life)

Contact a health care provider if you have questions about your health.

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Upon activation, TGF-1 plays a critical role in the ECM remodelling process and fibrogenesis, regulating the expression of MMPs and TIMPs and the deposition of critical ECM components

Together, they offer a complementary platform for studies centered on cellular migration, angiogenic signaling, and cytoskeletal modulation