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Ann Internal Med (2010) 153:14757

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Typical dosing schedule: Initial dose: 3 mg once daily for 30 days Maintenance doses may be increased based on treatment response Common higher dose: 14 mg once daily Administration guidelines: Take the tablet once daily on an empty stomach Swallow with a small amount of water Wait at least 30 minutes before eating, drinking, or taking other medicines Do not crush, chew, or split the tablet Always follow the prescribing physicians instructions for safe and effective treatment