For researchers studying gut-repair peptides and enterocolitis models, BPC 157 remains one of the most referenced compounds in the literature
It is likely that the larger number of statistically significant changes to the microbiome observed in the groups switched from WD to LD reflects their more numerous exposures to different diets, longitudinal changes in dietary exposure, the stress associated with diet switch, the negative energy state achieved by treatment and/or diet-driven weight loss, or a combination of these factors, but it may also be related to differences in terminal body weight and fat mass since both adiposity and diet composition have been shown to modulate the mouse gut microbiome profile
It also modulates nitric oxide pathways, helping regulate inflammation and blood flow
But I've never seen B12 ampoules available in the kind of smaller doses that would be needed to try this
In the majority of cases, people with elevated B12 feel completely normal, and the finding only appears on routine blood work