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PNPO-PLP axis senses prolonged hypoxia in macrophages by regulating lysosomal activity

Rapid weight loss on these medications causes a cascade of side effects: loss of skin elasticity (Ozempic face), muscle wasting, gut disruption, hair thinning, bone density loss, fatigue, and nutrient depletion

Your clinician can also advise on optimal timing and dosing to maximise symptom relief whilst maintaining the effectiveness of your weight management treatment

Taken together, for someone seeking a streamlined, research-aligned PCOS option rather than a general wellness inositol Wholesome Storys blend may be a strong fit

But, as mentioned, those studies were much too small to really know whether it is safe