The Connection Between Electrolytes and Muscle Retention One of the biggest concerns with rapid weight loss on GLP-1 medications is the loss of lean muscle mass
Weight begins creeping back within the first month
Among AOMs, tirzepatide is the most prescribed AOM medication
GLP-1 Side Effects at a Glance Nausea & vomiting Constipation Diarrhea Reflux & sulfur burps Loss of muscle and lean mass Skin, hair, and nail changes Fatigue, depression, and the blahs Dehydration Less Common but Serious Side Effects Pancreatitis and pancreatic cancer Gallstones & gallbladder disease Thyroid cancer Acute kidney injury Retinopathy, macular degeneration, and nonarteritic anterior ischemic optic neuropathy (NAION) Common GLP-1 Side Effects and How to Manage Them Most side effects show up early, often within the first few days of beginning GLP-1 treatment
For example, if injecting in the abdomen, you might use the upper right quadrant one week, lower right the next, then lower left, and upper left, before returning to the starting position