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What You Should Know GLP-1 medications reduce caloric intake and weight, but up to 45% of the weight lost may come from lean body mass rather than fat alone

Acknowledgements Graphical Abstract, Figure 1, and Figure 2 were created using Biorender

For those with obesity-related health concerns or uncontrolled Type 2 diabetes, this can be life-changing

That's why Ali recommends that all of his weight loss patients focus on eating plenty of protein and vegetables

As an example, in the DURATION-8 study, while combination therapy produced greater HbA1c and body weight reductions, the effect was less than additive compared to the sum of individual drug effects, most likely because the efficacy of glucose-lowering therapies can depend on baseline glycaemic control [24]