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Bone (2002) 30(1):30713.10.1016/S8756-3282(01)00662-7 17 Nuche-BerenguerBMorenoPEsbritPDapiaSCaeiroJRCancelasJet alEffect of GLP-1 treatment on bone turnover in normal, type 2 diabetic, and insulin-resistant states

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It is imperative for individuals to recognize contraindications linked with GLP-1 receptor agonistsparticularly those with personal or family histories of medullary thyroid cancer or multiple endocrine neoplasia syndrome type 2as there is an elevated risk associated with the development of malignant C-cell tumors

It is important to emphasize that although this meta-analysis brings promising data, there is a need for further research to confirm these findings and to better understand exactly how L-carnitine interacts with the mechanisms of diabetes