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It also plays a key role in the detoxification of heavy metals and environmental pollutants

[link] K Mueller, G Levesque-Tremblay, SA Braybrook, J Pelloux, "Tuning of pectin methylesterification: consequences for cell Wall biomechanics and development", Planta 242 (4): 791-811 (2015)

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doi: 10.1038/s41586-023-06269-0

To minimize these undesired effects, it is imperative to elucidate the mechanisms underlying hyperglucagonemia before translating GCGR antagonism into clinical practice